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The Position
The Opportunity
You will support MSAT process performance with the following tasks.
Analytical Method Comparability: Determine and validate the repeatability of a DMAc peroxide concentration dilution series using NMR.
Oxidation Impact Study: Analyze existing study data to design an experimental plan and assist in executing the scale-down model to assess methionine 255 oxidation under Kadcyla manufacturing conditions.
QC Method Transfer: Apply findings from the oxidation study to define a formal peroxide threshold, and support the transfer to Quality Control.
Final Handover: Provide comprehensive study plans, final reports, and SOP-compliant documentation covering the entire DMAc peroxide evaluation.
Support for digitalization initiatives, e.g., the implementation of a PM parameter report.
Who You Are
You hold a Master's degree (completed in the last 12 months) in biochemistry, biotechnology, or chemical engineering; or are currently enrolled in your Master’s programme.
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You speak fluent English and German.
Strong familiarity with analytical chemistry techniques (including NMR and quantitative assays) as well as protein degradation mechanisms (such as oxidation).
Please note that due to cantonal regulation reasons, NON-EU/-EFTA nationals need to provide a confirmation by their university stating that an internship is mandatory for their studies.
Ready to take the next step? We'd love to hear from you. Apply now to explore this exciting opportunity!
Who we are
A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let’s build a healthier future, together.
Roche is an Equal Opportunity Employer.
