Responsibilities
Lead, mentor, and grow Profluent’s software engineering team, with responsibility for technical direction, hiring, organizational development, and execution
Own the roadmap for software and data engineering, balancing scientific impact, user needs, delivery speed, scalability, and long-term platform strategy
Define the software and data architecture, system boundaries, and data flows connecting computational design, high-throughput experimentation, analysis, and machine learning
Architect and guide delivery of scientist-facing applications and data systems supporting experimental design, sample tracking, laboratory automation, assay data capture, and analysis
Establish scalable data models and standards for identifiers, provenance, lineage, versioning, interoperability, and access control, ensuring experimental results are reliable, reusable, and model-ready
Partner across science, automation, bioinformatics, data science, and ML while establishing strong engineering and product practices that drive reliable delivery and adoption
Qualifications
8+ years of software engineering experience, including 3+ years managing or leading engineers
BS, MS, or PhD in Computer Science, Bioengineering, Computational Biology, or a related field, or equivalent practical experience
Track record of leading teams that architect and deliver production-quality, data-intensive software platforms
Strong technical foundation in Python, backend systems, databases, APIs, cloud infrastructure, and modern software development practices
Experience designing data architectures, schemas, and domain models for complex scientific, experimental, or similarly interconnected workflows
Demonstrated ability to translate ambiguous user and scientific needs into reliable systems, make sound technical and product tradeoffs, and drive adoption
Preferences
Experience building scientific data infrastructure, research software, LIMS integrations, or scientist-facing applications
Experience with Benchling, laboratory automation, instrument integration, sample tracking, or high-throughput experimental platforms
Experience connecting experimental workflows with downstream analysis and machine learning
Familiarity with biological data from protein engineering, gene editing, sequencing, screening, or mammalian or bacterial systems
Frontend development experience and an interest in building intuitive scientist-facing interfaces
What We Offer
High-growth opportunity with meaningful impact on the future of protein design
Competitive compensation package with equity participation
401(k) with a strong employer match
Comprehensive benefits including health/dental/vision insurance
Generous PTO policy and commitment to work-life balance
Professional development opportunities in a cutting-edge field at the intersection of AI and biology
Profluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.
Work Authorization Requirement
Applicants must have ongoing work authorization in the United States that does not require employer sponsorship. Sponsorship will not be provided now or at any time in the future for this position.
Employment Eligibility Verification
Legal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire.
Hiring Salary Range
$268,000—$355,000 USD
NOTICE TO STAFFING AND SEARCH FIRMS: Profluent does not accept unsolicited candidate submissions. We ask that agencies refrain from sending resumes to our careers inbox, hiring managers, or any Profluent employee. Any resume submitted without a signed agreement and an active search request from our Talent team will be treated as the property of Profluent, and no placement fee will be owed.
