Responsibilities
Assay & Method Development: Develop and extend current assays to better fit evolving clinical needs, with support from scientists, engineers, and other technical staff
Computational Data Analysis: Apply the analytical and computational methods used in current assays, and build upon them to enable new capabilities; develop, implement, and use software tools to quantitatively analyze experiments and processes, requiring moderate proficiency in R or Python
Validation & Regulatory Compliance: Support assay validations and derisking under regulatory and design control frameworks (FDA, MolDx, etc.)
Scientific Communication: Present technical findings and project updates verbally at group meetings and via internal written reports
Wet Lab Execution: Carry out experiments in lab and document experimental procedures and results, and contribute to routine organization of the R&D lab
Tech Transfer: Partner across departments to transfer and scale developed assays and workflows into high-throughput clinical laboratory operations.
Troubleshooting & Root Cause Analysis: Apply sound engineering practices to scale, optimize, and improve molecular biology methods; systematically identify and investigate root sources of variation to develop short-term corrections and long-term preventative measures
Requirements
Bachelor’s, Master’s, or equivalent degree in Molecular Biology, Biochemistry, Cell Biology, Microbiology, Biophysics, or related fields
At least 12 months of experience with molecular biology techniques (e.g. PCR, electrophoresis, DNA purifications) in a research or clinical laboratory (can be during or after Bachelor’s degree)
Solid foundation in quantitative data analysis, statistics, and experimental design, with familiarity using R or Python (and a strong willingness to expand computational skills).
Clear verbal and written communication skills in reporting to cross-functional teams of scientists and non-scientists
Proven experimental troubleshooting and root-cause analysis skills with sharp attention to detail
Nice-To-Haves
Start-up experience
Experience with next-generation sequencing (NGS) and/or cell-free DNA
Previous experience with liquid handling or other laboratory automation
Knowledge of molecular oncology
Experience with composing protocols of standard molecular biology techniques
Benefits And Perks
Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)
Free daily on-site lunches provided from top eateries
A variety of perks on campus (shuttle to and from select transit hubs, state of the art gym, restaurant)
Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses) (2) generous equity options offering, on top of (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid paternal leave etc.).
For this position, we offer a total compensation package of $105,737 per year, including a base pay range of $76,155 - $87,034 per year.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
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BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact
- Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
- Unity Confirm™ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne’s Fetal Cell Capture™ Technology.
- Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth
From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition
Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future
Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.
Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com
